Centrophenoxine main effect in the cerebral cortex, it can promote the REDOX of brain cells, regulating the metabolism of the nerve cells, increase the use of sugar to the inhibition of the central nervous excitement. Children traumatic coma, nocturia, disturbance of consciousness, senile psychosis, all kinds of dementia, alcohol, etc.
Preparation: anhydrous glacial acetic acid (calculated on water content, each 1 g 5.22 mL) of water and acetic anhydride, 750 mL, add perchlorate (70% 72%) 8.5 mL, shake well, slowly add acetic anhydride at room temperature of 23 mL, and while shaking, and after the vibration shake well again, put the cold, add right amount to make anhydrous glacial acetic acid into a 1000 mL, shake well, 24 hours a day. If the test of the acetylation, the water must be a determination method of determination of moisture content on this page, and then water and acetic anhydride to adjust to the liquid water content of 0.01% to 0.01%.
Calibration: take benchmark in 105 ℃ drying to constant weight is about 0.16 g, potassium hydrogen phthalate precision said, with no water 20 ml glacial acetic acid to dissolve, and liquid crystal violet indicator 1 drop, using the liquid slowly titration to blue, and the result of the titration correction by blank test. Each 1 ml perchloric acid titration fluid (0.1 mol/L) is equivalent to 20.42 mg of potassium hydrogen phthalate. According to the consumption of the liquid and the extraction of potassium hydrogen phthalate dosage, calculate the liquid concentration, can.
Storage: brown glass bottle, airtight preservation.
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