Palonosetron Hydrochloride

Palonosetron Hydrochloride is a white to fair apparent powder. It is readily acrid in water, acrid in propylene glycol, and hardly acrid in booze and 2-propanol.

Aloxi (palonosetron hydrochloride) is a agency of anti-emetic and anti-nausea. It is serotonin-3 (5-HT3) receptor adversary with a top bounden affection for this receptor.

Aloxi bang is in 5 ml disposable canteen or 1.5 ml alone use canteen available. Each canteen contains 5 ml to 0.25 mg of abject as palonosetron hydrochloride 0.28 mg palonosetron, 207.5 mg mannitol, disodium edetate, and citrate absorber in baptize for intravenous administration.

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What is Palonosetron?

Palonosetron (INN, barter name Aloxi) is a 5-HT3 adversary in the blockage and analysis of chemotherapy-induced abhorrence and airsickness (CINV). It is acclimated for the ascendancy of delayed CINV-nausea and vomiting, and there is basal affirmation suggests that it may be bigger than granisetron.

Palonosetron is administered one hour intravenously as a alone dosage 30 account above-mentioned to chemotherapy or as a alone articulate abridged afore chemotherapy.Use articulate conception August 22 accustomed in 2008 for the blockage of astute CINV alone ample analytic balloon showed no articulate administering as able as intravenous to be acclimated adjoin the delayed CINV.

To learn more: Palonosetron Hcl

visit: Pharmaceutical Ingredients