Sunday, December 29, 2013

What is chlortetracycline?


Aureomycin, also known as "chlortetracycline," was the first discovered tetracycline class of antibiotics. Dr Benjamin in 1945 featured from the university of Missouri SangBo plots collected soil samples isolated from Streptomyces golden (Streptomyces aureofaciens), named "aureomycin".
Antibacterial wide range, for a variety of bacteria, some patients, mycoplasma, helix and parasite inhibition; Mainly used for bacterial infections resistant to penicillin, such as pneumonia and staphylococcus aureus sepsis, typhus, mycoplasma pneumonia, amebic dysentery, etc.
Easy to cause the gastrointestinal tract after oral effects such as nausea, vomiting, diarrhea, etc.; And chlortetracycline and broad spectrum antibiotic use in a long time, because of the sensitive bacteria are destroyed, cause not sensitive bacteria or fungi blooms, which can lead to staphylococcus aureus, candida double infection, etc.
Aureomycin can combine with tRNA, so as to achieve the effect of bacteriostasis. Often used as a veterinary drug used to treat conjunctivitis.


Friday, December 27, 2013

Information about Cholesteryl benzoate (Cholesterol benzoate)



Product Name: Cholesteryl benzoate
Synonyms: 3-Benzoyloxycholest-5-ene;3-Hydroxycholest-5-ene3-benzoate;Cholest-5-en-3-ol (3beta)-, benzoate;Cholest-5-en-3-ol(3.beta.)-,benzoate;Cholest-5-en-3-yl benzoate;Cholest-5-ene-3-ol3-benzoate;CHOLESTERYL BENZOATE;CHOLESTEROL BENZOATE
CAS: 604-32-0
MF: C34H50O2
MW: 490.76
EINECS: 210-064-3
Product Categories: Cholesteryl Compounds (Liquid Crystals);Functional Materials;Liquid Crystals & Related Compounds;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;CholestericAsymmetric Synthesis;Chiral Building Blocks;Complex Molecules;Liquid Crystals;Organic Electronics and Photonics;Asymmetric Synthesis
Mol File: 604-32-0.mol



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Thursday, December 26, 2013

The role of Ceftazidime with purpose



Ceftazidime of the third generation of semisynthetic cephalosporins. Products for free acid (five carbohydrates), and with a certain amount of anhydrous sodium carbonate, made into injection for use. Suitable for sensitive gram-negative bacillus by sepsis, infection of lower respiratory infection, abdominal bile, complexity, urinary tract infections and severe skin soft tissue infection.
The goods to the third generation of cephalosporin class of antibiotics, antibacterial activity is stronger, has a wide antimicrobial spectrum, the gram positive or negative has strong effect. Of gram positive bacteria, negative bacteria produce beta lactamase with high stability, and the goods of pseudomonas aeruginosa, escherichia coli, white clay, bacillus proteus, enterococcus, salmonella, shigella bacteria, neisseria gonorrhea, neisseria meningitidis, s. aureus bacteria produce gas, hemolytic streptococcus, pneumococcus and bacillus has strong antimicrobial activity, such as especially for pseudomonas aeruginosa strongest antibiotics.
Can be used for the treatment of infection or by two or more mixed infection caused by sensitive bacteria. Mainly used for clinical sepsis, bacteremia, bronchitis, pneumonia, pleurisy, peritonitis, pyelonephritis, urinary tract infections, prostatitis, cystitis, ear nose and throat infections, skin and soft tissue infections, bone and joint infection, pelvic inflammation and burns, etc.

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Tuesday, December 24, 2013

What is Human serum albumin?



Human Serum Albumin, hereinafter referred to as HSA is the protein in Human plasma and its non glycosylation of single polypeptide contains 585 amino acids, the molecular weight of 66 kd. In its concentration in plasma of 42 g/L, about 60% of the plasma total protein. Human serum albumin in body fluids can transport fatty acids, bile pigment, amino acids, steroids, metal ions, and many therapeutic molecules, such as: while maintaining normal blood osmotic pressure. In clinic can be used in the treatment of burn shock and human serum albumin, used to supplement for surgery, an accident or bleeding caused by blood loss, also can be used as compatibilizer in the plasma.

Thursday, December 19, 2013

Centrophenoxine pharmaceutical analysis



Centrophenoxine main effect in the cerebral cortex, it can promote the REDOX of brain cells, regulating the metabolism of the nerve cells, increase the use of sugar to the inhibition of the central nervous excitement. Children traumatic coma, nocturia, disturbance of consciousness, senile psychosis, all kinds of dementia, alcohol, etc.
Preparation: anhydrous glacial acetic acid (calculated on water content, each 1 g 5.22 mL) of water and acetic anhydride, 750 mL, add perchlorate (70% 72%) 8.5 mL, shake well, slowly add acetic anhydride at room temperature of 23 mL, and while shaking, and after the vibration shake well again, put the cold, add right amount to make anhydrous glacial acetic acid into a 1000 mL, shake well, 24 hours a day. If the test of the acetylation, the water must be a determination method of determination of moisture content on this page, and then water and acetic anhydride to adjust to the liquid water content of 0.01% to 0.01%.
Calibration: take benchmark in 105 ℃ drying to constant weight is about 0.16 g, potassium hydrogen phthalate precision said, with no water 20 ml glacial acetic acid to dissolve, and liquid crystal violet indicator 1 drop, using the liquid slowly titration to blue, and the result of the titration correction by blank test. Each 1 ml perchloric acid titration fluid (0.1 mol/L) is equivalent to 20.42 mg of potassium hydrogen phthalate. According to the consumption of the liquid and the extraction of potassium hydrogen phthalate dosage, calculate the liquid concentration, can.
Storage: brown glass bottle, airtight preservation.

Tuesday, December 17, 2013

Information about Chlorhexidine diacetate

To associate the after-effects of an in vitro abstraction with analytic response, the furnishings of 0.005 and 0.05% chlorhexidine diacetate and 0.1 and 1.0% povidone-iodine concentrations on anguish healing were evaluated in 5 advocate dogs. Full-thickness derma wounds (2 X 2 cm) were anhydrous already circadian for 14 canicule with the antibacterial solutions or physiologic-buffered saline. Chlorhexidine diacetate 0.05% had decidedly added antibacterial action than povidone-iodine and saline, and both chlorhexidine diacetate concentrations had balance furnishings 6 hours afterwards irrigation. Neither povidone-iodine nor acrid had cogent antibacterial activity. The percentages of unhealed anguish breadth and anguish abbreviating were affected 7, 14, and 21 canicule afterwards wounding. Healed anguish breadth and abbreviating were agnate in wounds advised with chlorhexidine diacetate and povidone-iodine. However, wounds advised with chlorhexidine diacetate had added healed anguish breadth on canicule 7 and 14 and added abbreviating on canicule 7, 14, and 21 than saline-treated wounds. At the concentrations tested, chlorhexidine diacetate irrigations provided antibacterial action and were added benign to anguish healing than irrigations with acrid alone. These after-effects advance that concentrations of chlorhexidine diacetate which are cytotoxic to tissue ability fibroblasts in vitro do not baffle with anguish healing in vivo. 

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From:pharmaceutical chemicals

Thursday, December 12, 2013

Monobenzone pharmacology



4-(Benzyloxy)phenol, or Monobenzone, is an amoebic actinic in the phenol ancestors with actinic blueprint C13H12O2.[1][2] It is acclimated as a contemporary biologic for medical depigmentation.
Pharmacology:The contemporary appliance of monobenzone in animals decreases the elimination of melanin from melanocytes. The aforementioned activity is anticipation to be amenable for the depigmenting aftereffect of the biologic in humans. Monobenzone may could cause abolition of melanocytes and abiding depigmentation.
The analysis of the derma afterwards depigmentation with contemporary monobenzone is the aforementioned as that apparent in vitiligo; the covering is accustomed except for the absence of identifiable melanocytes. Therefore, monobenzone is acclimated as a contemporary anesthetic to assuredly depigment accustomed derma surrounding vitiliginous lesions alone in patients with broadcast (greater than 50 percent of physique apparent area) idiopathic vitiligo.Monobenzone is aswell getting advised for the analysis of Melanoma.


The use of Amiodarone Hydrochloride



Amiodarone hydrochloride as an angina pectoris medicine, can selectively dilate coronary blood flow, reduce myocardial oxygen consumption at the same time, slow heart rate, reduce the atrioventricular conduction velocity is similar to the effects of beta blockers.
Description: white to light yellow crystalline powder, odourless, tasteless, melting point of 153 ~ 158 ℃. Soluble in chloroform, soluble in ethanol, slightly soluble in acetone, insoluble in water.
Function and use: this medicine for angina pectoris medicine, resistance to selectively dilate coronary blood flow, reduce myocardial oxygen consumption at the same time, slow heart rate, reduce the atrioventricular conduction velocity is similar to the effects of beta blockers. Sex and ventricular tachycardia is used in room, paroxysmal atrial flutter and fibrillation, pre-excitation syndrome syndrome, also used for refractory paroxysmal tachycardia chronic coronary artery insufficiency and angina, etc.
Usage: adult oral: start 200 mg each time, 3 times a day, after a meal, after a week to maintain volume, 100 mg/time, 2-3 times a day.
Side effects: gastrointestinal symptoms: nausea, vomiting, dry mouth, abdominal distention, constipation, loss of appetite, etc. Was observed in the cardiovascular system: sinus bradycardia, sinus arrest or sinus atrial block atrioventricular block. Occasional hyperthyroidism, drug rash, itching, there is also a cornea pigmentation and pigmentation of the skin.
Taboo: room ventricular conduction block and bradycardia were banned.

Monday, December 9, 2013

The introduction of Amoxicillin



Amoxicillin, also known as Ann mo del or "Westwood, is one of the most commonly used penicillin kind of broad spectrum beta lactam antibiotics, as a kind of white powder, has a half-life of about 61.3 minutes. Stable under acid condition, gastrointestinal absorption rate of 90. Amoxicillin antiseptic effect is strong, strong ability to penetrate the cell membrane also. Is one of the widely used oral penicillin, the preparation of capsules, tablets, granules, tablets, etc. Penicillin allergy and penicillin skin test positive patients disabled.
Description: white or white crystalline powder; Taste slightly bitter. This product is slightly soluble in water, hardly soluble in ethanol. This product acid, in the gastrointestinal tract absorb good, and not easily affected by the most food. Fiber will affect the absorption, reduce the efficacy. Don't eat high-fiber foods during taking the drug, such as oats, celery, carrots, etc.

Thursday, December 5, 2013

what are the ingredients of the Inositol




Inositol is an animal, microbial growth factor. Molecular formula (CHOH) 6. Also called cyclohexanol six alcohol, widely distributed in plants and animals. The first isolated from the heart and liver. Cyclohexanol six alcohol in nature, there are several suitable isomers, but valuable, naturally occurring isomers of cis - 1, 2, 3, 5 - anti - 4, 6 - cyclohexanol six alcohol, structural formula as above. At above 80 ℃ from water or acetic acid of inositol is white crystal, melting point 253 ℃, the density of 1.752 g/cm 3 (15 ℃), sweet taste, soluble in water and acetic acid, and no optical activity. Can be made of corn soaking liquid extract. Mainly used in the treatment of cirrhosis, hepatitis, fatty liver and high blood cholesterol in disorder.
Also called cyclohexanol six alcohol. In chemistry is considered to be a multiple alkyl cyclohexane derivatives. Nine possible isomers in theory, commonly found in nature, there are four, respectively called D - chiro - inositol, L - chiro - inositol, muscle (MYO - inosi - tol) and inositol shark inositol (scyllo - inositol). One of the most common in nature is muscle inositol. D - chiro - inositol and L - chiro - inositol quantity is less, but distribution is very wide, can become the majority of methyl ether. Inositol in coconut, shark, mammals can be found in the urine. In general inositol is widespread, but on its metabolic pathways or physiological function is not very clear.


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From:Natural herbal extracts

Wednesday, December 4, 2013

The purpose of Atorvastatin Calcium




Atorvastatin Calcium to treat its total cholesterol, low density lipoprotein cholesterol and apolipoprotein B rise and elevated triglycerides. Patients with primary hypercholesterolemia, including familial hypercholesterolemia (heterozygous type) or mixed hyperlipidemia (Fredrickson taxonomy Ⅱ type a and b Ⅱ) patients, if diet therapy and other non-drug therapy efficacy are not satisfied, can be used this product. The homozygous familial hypercholesterolemia patients, atorvastatin calcium can share with other lipid-lowering therapy or used alone (when no other treatments), in order to reduce total cholesterol and low density lipoprotein cholesterol.

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From:pharmaceutical chemicals

Tuesday, December 3, 2013

What is Memantine?



Memantine is the aboriginal in a atypical chic of Alzheimer's ache medications acting on the glutamatergic arrangement by blocking NMDA receptors. It was aboriginal actinic by Eli Lilly and Company in 1968. Memantine is marketed beneath the brands Axura and Akatinol by Merz, Namenda by Forest, Ebixa and Abixa by Lundbeck and Memox by Unipharm. Memantine has been apparent to accept a bashful aftereffect in moderate-to-severe Alzheimer's ache and in dementia with Lewy bodies.Despite years of research, there is little affirmation of aftereffect in balmy Alzheimer's disease.


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From:Natural herbal extracts