Some information about Histrelin Acetate

Histrelin Acetate is an effective, long-lasting and synthetic non-peptide gonadotropin-releasing hormone analogues. It is more than endogenous gonadotropin-releasing hormone more effective. Long-term use of gonadotropin-releasing hormone agonists can reduce the number of pituitary gonadotropin receptors, also inhibits gonadotropin receptor stimulation. In the ovary, gonadotropin-releasing hormone agonist suppression steroid substances produced and reducing the number of gonadotropin receptors. Histrelin Acetate for central precocious puberty. Give proper daily dose of histrelin with central precocious puberty in boys make gonadotropin levels fall and testicular nucleic acids decrease. The girl in serum estradiol concentrations decreased to prepubertal levels, cessation of menstruation, linear growth, skeletal maturation and adult slow increase in height.

There are some indications that melatonin is involved in puberty. Nevertheless, with the Histrelin Acetate central precocious puberty in girls with estrogen reduced, but did not decrease the concentration of melatonin.

Indications:
For the treatment of central precocious puberty. Can also be used to treat endometriosis, polycystic ovarian disease, uterine leiomyoma. Also with estrogen or progesterone combined therapy of severe pre-menopausal syndrome. FDA alone can prevent acute intermittent porphyria.

Adverse reactions:
Clinical Trials common adverse reactions were injection site skin reactions (erythema, swelling and itching), vaginal bleeding, urticaria, purpura, convulsions frequency increases, visual clutter, hot flushes / flushing, swelling, mood changes, and behavioral disorder and fever , limb pain, fatigue, chills, malaise, neck, chest or trunk pain and viral infections, weight gain, head / facial pain, nausea and vomiting.

Contraindications:
Pregnant or potentially pregnant women and lactating women disabled histrelin. Hypersensitivity reaction to the drug people are disabled.



More about:Histrelin Acetate suppliers
From:natural food additive