Sulfaguanidine is a dihydrofolate reductase (DHFR) inhibitor. Sulfonamides are adjoin gram-positive and gram-negative bacteria.Sulfaguanidine a sulfa antibacterial which blocks the amalgam of dihydrofolic acid by inhibiting dihydropteroate synthase agitator in the bacteria. Resistance approach by alteration the dihydropteroate synthase or an another avenue for folic synthesis.Sulfaguanidine accept done to be decidedly able in preventing the advance of Gram-negative bacilli intestinal. It is a advantageous apparatus for the inhibition of the amalgam of comestible factors of abdominal bacteria.
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