Most of histamine in the physique is in granules of mast beef and the white claret cells, basophils and mast beef is generated -eosinophils.Non histamine in several tissues, including the brain, area it acts as a neurotransmitter.
Mast beef are abnormally abundant at sites of abeyant abrasion - the nose, aperture and feet, centralized physique surfaces, and claret vessels. Assertive amines and alkaloids, including drugs such as morphine and curare alkaloids, can displace histamine in granules and could could cause its release.
Another important website of histamine accumulator and absolution of enterochromaffin-like (ECL) beef of the stomach.The capital pathophysiological apparatus of mast beef and basophil histamine absolution is immunological.
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